Scicon-MR (30mg) 20 Tablets

Gliclazide is a second-generation sulfonylurea drug that primarily acts by stimulating insulin release from pancreatic beta cells. It selectively binds to sulfonylurea receptors on the beta cell membrane, leading to the inhibition of ATP-sensitive potassium channels. This inhibition causes depolarization of the cell membrane, which opens voltage-gated calcium channels, allowing calcium influx. The resulting increase in intracellular calcium triggers insulin secretion. Gliclazide also enhances the effect of insulin by improving insulin receptor sensitivity and promoting peripheral glucose uptake, thereby reducing blood glucose levels.

Gliclazide 30mg

Sulfonylurea.

Tablet

The following are the uses of Gliclazide 30mg Tablet:

• Used for treating Type 2 diabetes
• Used to help lower high blood sugar levels
• Used to improve insulin production in the body
• Used to manage blood sugar levels after meals
• Used to reduce the risk of diabetes-related complications
• Used as part of a comprehensive diabetes management plan
• Used in combination with diet and exercise for effective blood sugar control
• Used to help prevent long-term damage to organs affected by high blood sugar

Follow these dosage instructions:

• Take as per doctor's Prescription.
• Take one tablet per day as your doctor suggests.
• Your doctor will determine the treatment length based on your symptom severity.

In the case of an overdose of Gliclazide 30mg Tablets, the individual may experience symptoms such as severe hypoglycemia, characterized by dizziness, sweating, and confusion. It is important to recognize the signs of an overdose, which can include seizures, loss of consciousness, and difficulty breathing. Prompt medical intervention is necessary to manage the overdose effectively, including the administration of glucose to stabilize blood sugar levels and prevent further complications. Immediate contact with a healthcare professional or emergency services is crucial.

In the case of a missed dose of Gliclazide 30mg Tablet, it is recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. It is important not to double the dose to make up for a missed one. If you frequently miss doses, it is advisable to set reminders or use a pill organizer to help you stay on track with your medication regimen. Always consult your healthcare provider if you have any concerns or questions regarding missed doses.

To take Gliclazide 30mg Tablet, swallow the tablet whole with a glass of water, preferably in the morning before breakfast, following the dosage instructions provided by your healthcare professional, and do not crush or chew the tablet.

Here are the conditions or situations when Gliclazide 30mg Tablet should not be taken:

• Do not take if you are allergic to sulfonylureas or any of the tablet's components.
• Contraindicated in patients with type 1 diabetes mellitus or diabetic ketoacidosis.
• Should not be used if you have severe liver or kidney disease.
• Not recommended for individuals with a known sensitivity or reaction to sulfonamides.
• Avoid if you have a history of blood disorders or blood-related conditions.
• Do not take if you are pregnant or breastfeeding, unless advised by a healthcare professional.
• Should not be used in patients with a known deficiency of glucose-6-phosphate dehydrogenase (G6PD).
• Contraindicated in individuals with a history of severe gastrointestinal problems or blockage.
• Not suitable for those with a history of alcohol abuse or severe infection.

The side effects of Gliclazide 30mg Tablet may include:

• Hypoglycemia (low blood sugar)
• Nausea and vomiting
• Stomach pain or discomfort
• Diarrhea or constipation
• Skin rashes or itching
• Dizziness or lightheadedness
• Headache
• Visual disturbances, such as blurred or double vision

Following are the precautions and warnings for Gliclazide 30mg Tablet:

• Not recommended for individuals with a known allergy to Gliclazide or related sulfonylurea drugs.
• Requires careful monitoring in patients with kidney or liver problems, as dosage adjustments might be necessary.
• Patients with a history of diabetic ketoacidosis should exercise caution, as it may precipitate its recurrence.
• May cause hypoglycemia, especially in cases of irregular meals or increased physical activity. Regular blood glucose monitoring is essential.
• Elderly patients may be more susceptible to hypoglycemic effects and should be monitored closely.
• Should be used with caution in individuals with thyroid, adrenal, or pituitary disorders.
• Always carry glucose tablets or a sugary snack to treat hypoglycemic episodes promptly.

Following are the drug interactions for Gliclazide 30mg Tablet:

• Co-administration with other sulfonylureas or insulin may increase the risk of hypoglycemia, requiring careful monitoring of blood glucose levels.
• The effect of hypoglycemia can be prolonged when used with beta-blockers, MAO inhibitors, or ACE inhibitors.
• Gliclazide may interact with certain antibiotics like rifampicin and chloramphenicol, reducing its blood glucose-lowering effect.
• Alcohol consumption can enhance the hypoglycemic effect, potentially leading to severe hypoglycemia.
• Caution is advised when using with drugs that affect liver function, as it may alter Gliclazide's metabolism.
• Non-steroidal anti-inflammatory drugs (NSAIDs) and certain steroid medications can reduce the glucose-lowering effect of Gliclazide.
• Fluconazole, a common antifungal medication, can increase Gliclazide levels in the body, potentially leading to hypoglycemia.

Following are the food interactions for Gliclazide 30mg Tablet:

• Avoid excessive alcohol consumption while taking this medication as it can interfere with blood sugar control and increase the risk of hypoglycemia.
• Grapefruit and grapefruit juice should be consumed with caution as they may affect the metabolism of Gliclazide, leading to increased drug levels and potential side effects.
• Maintain a consistent carbohydrate intake, as sudden changes in diet can impact blood sugar levels.
• Avoid high-sugar foods and beverages, as they can cause rapid spikes in blood glucose.
• Consume a balanced diet rich in whole grains, lean proteins, fruits, and vegetables to support overall health and diabetes management.
• Be cautious with high-fat meals, as they may delay the absorption of Gliclazide.
• Follow a structured meal plan as advised by your healthcare provider to optimize the medication's effectiveness.
• Always consult your doctor or dietitian for personalized dietary recommendations while taking Gliclazide.

Gliclazide 30mg Tablets should be stored in a cool and dry place, preferably at room temperature, ensuring it is protected from light and moisture. Keep the tablets in their original packaging, tightly sealed, to maintain their integrity and effectiveness. Avoid storing them in the bathroom or kitchen cabinets, as these areas can be prone to heat and humidity. Always check the expiration date, and never use the medication beyond this date. When it comes to disposal, do not flush the tablets down the toilet or throw them into the trash. Instead, follow local guidelines for pharmaceutical waste disposal or consult a pharmacist for guidance on how to safely dispose of unused or expired Gliclazide tablets, ensuring they do not cause harm to the environment or others. Keep all medications securely stored and out of the reach of children to prevent accidental consumption.

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Following are the quick tips for Gliclazide 30mg Tablet:

• Take the tablet as directed by your doctor, typically with or after meals.
• Swallow the tablet whole without crushing or chewing for optimal absorption.
• Maintain a consistent dosing schedule to keep your blood sugar levels stable.
• Avoid alcohol consumption as it may affect blood sugar control.
• Regularly monitor your blood sugar levels as advised by your healthcare provider.
• Inform your doctor about all medications you are taking to prevent potential drug interactions.
• Store the tablets in a cool, dry place, away from direct sunlight and moisture.