Solifen (10mg) 10 Tablets

Solifen (10mg) 10 Tablets

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  • Manufacturer GETZ PHARMACEUTICALS (PVT.) LTD.
  • Generic Name Solifenacin Succinate

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • Dosage
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Quick Tips, if any
  • Laboratory Screening
  • Description

    Solifenacin Succinate 10mg Tablet primarily exerts its therapeutic effects by acting as a selective antagonist of muscarinic acetylcholine receptors, specifically targeting the M3 receptor subtype. This mechanism of action is crucial in managing overactive bladder symptoms. By blocking the M3 receptors in the detrusor muscle of the bladder, Solifenacin Succinate inhibits the binding of acetylcholine, a neurotransmitter that stimulates bladder contractions. This blockade reduces the involuntary contractions of the bladder, leading to increased bladder capacity and improved urinary control. This targeted action on the M3 receptors helps to alleviate symptoms associated with overactive bladder, such as urgency, frequency, and urge incontinence, without affecting other muscarinic receptor functions in the body.

  • Ingredients

    Solifenacin Succinate
  • Drug Class

    Anticholinergic.

  • Dosage Form

    Tablet

  • Uses

    The following are the uses of Solifenacin Succinate 10mg Tablet:

    • Used for overactive bladder symptoms, reducing frequent and uncontrolled urges to urinate.
    • Used to treat bladder contractions, helping to relax the bladder muscles.
    • Used in managing urinary incontinence, improving bladder control.
    • Used to alleviate bladder discomfort and frequent urination.
    • Used to improve quality of life for patients with bladder issues.
    • Used as a long-term treatment option for bladder conditions.
  • Dosage

    Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

    • Overactive Bladder (OAB), 1 tablet once a day, preferably at bedtime.
    • Benign Prostatic Hyperplasia (BPH), 1 tablet once a day, preferably at bedtime.
  • In case of Overdose

    In the case of an overdose of Solifenacin Succinate 10mg Tablets, individuals may experience severe side effects, including blurred vision, dry mouth, and difficulty urinating. More serious symptoms can include rapid heartbeat, confusion, and seizures. It is important to seek medical assistance promptly if an overdose is suspected, as healthcare professionals can provide appropriate treatment and support to manage these symptoms effectively. Timely intervention can help mitigate potential health risks associated with an overdose of this medication.

  • Missed Dose

    In the case of a missed dose of Solifenacin Succinate 10mg Tablet, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Avoid taking extra medicine to make up for a missed dose, as this may increase the risk of side effects. It is important to maintain a consistent dosing routine, but if you frequently miss doses, consult your healthcare provider for advice on how to manage your medication schedule effectively.

  • How To Use

    To take Solifenacin Succinate 10mg Tablet, swallow the tablet whole with a glass of water, preferably at the same time each day, as directed by your healthcare professional, without crushing or chewing.

  • When Not to Use

    Here are the conditions and situations when Solifenacin Succinate 10mg Tablet should not be taken:

    • Should not be used in individuals with a known allergy to Solifenacin Succinate or any of its components.
    • Contraindicated in patients with untreated or uncontrolled narrow-angle glaucoma.
    • Not recommended for individuals with severe kidney disease or those on dialysis.
    • Should not be used in patients with a history of urinary retention or gastric retention.
    • Contraindicated in patients with a condition called myasthenia gravis.
    • Not suitable for individuals with severe constipation.
    • Avoid using this medication if you have a blockage in your stomach or intestines.
    • Do not use if you have a condition called toxic megacolon.
  • Side Effects

    The side effects of Solifenacin Succinate 10mg Tablet may include:

    • Dry mouth
    • Constipation
    • Blurred vision or other visual disturbances
    • Dizziness or lightheadedness
    • Fatigue and weakness
    • Headache
    • Stomach pain or upset
    • Difficulty urinating
  • Precautions & Warnings

    Following are the precautions and warnings for Solifenacin Succinate 10mg Tablet:

    • Not recommended for individuals with known hypersensitivity or allergy to Solifenacin or any other ingredients in the tablet.
    • Patients with narrow-angle glaucoma should exercise caution and inform their healthcare provider before using this medication.
    • May cause blurred vision or dizziness; patients should be cautious when performing activities that require clear vision and alertness.
    • Elderly patients may be more susceptible to side effects, particularly related to the central nervous system.
    • Use with caution in patients with kidney or liver disease, as dosage adjustments might be necessary.
    • Avoid alcohol consumption while taking this medication as it may increase the risk of side effects.
    • Patients with a history of gastrointestinal obstruction or urinary retention should use this medication with care and under medical supervision.
  • Drug Interactions

    Following are the drug interactions for Solifenacin Succinate 10mg Tablet:

    • It can interact with other anticholinergic medications, such as benztropine or diphenhydramine, leading to increased side effects like dry mouth, blurred vision, and constipation.
    • Concomitant use with potassium-sparing diuretics (e.g., spironolactone, amiloride) may cause hyperkalemia.
    • Solifenacin may decrease the absorption of ketoconazole, a type of antifungal medication, requiring a dose adjustment.
    • Avoid combining with strong CYP3A4 inhibitors like ketoconazole or clarithromycin, as it can increase Solifenacin levels and side effects.
    • The effectiveness of Solifenacin may be reduced when used with strong CYP3A4 inducers such as rifampin or St. John's Wort.
    • Use with caution alongside medications that prolong the QT interval (e.g., pimozide, quinidine), as this combination may increase the risk of cardiac arrhythmias.
    • Alcohol consumption may enhance the sedative effects of Solifenacin, potentially affecting alertness and coordination.
  • Food Interactions

    Following are the food interactions for Solifenacin Succinate 10mg Tablet:

    • Alcohol consumption should be limited as it can increase the risk of side effects like dizziness and drowsiness, especially when combined with the medication's sedative properties.
    • Avoid grapefruit and grapefruit juice as they can interfere with the medication's metabolism, leading to increased drug levels in the blood and potentially causing adverse effects.
    • Consuming high-fat meals may delay the absorption of Solifenacin, resulting in a potential decrease in its effectiveness.
    • Avoid caffeine or reduce intake as it can increase bladder activity and work against the medication's purpose of reducing bladder contractions.
    • Stay hydrated by drinking plenty of water, as this medication can cause dry mouth and maintaining hydration is important for overall health.
    • Avoid or limit spicy foods as they may irritate the bladder and worsen urinary symptoms, especially in individuals with sensitive bladders.
    • There is no specific dietary restriction, but maintaining a balanced diet is recommended to support overall health while taking this medication.
    • Always consult your healthcare provider for personalized advice regarding diet and medication interactions.
  • Storage/Disposal

    Solifenacin Succinate 10mg Tablets should be stored in a secure and dry location, ensuring they are kept away from moisture and heat. The ideal storage temperature for these tablets is room temperature, maintaining a consistent climate. It is crucial to keep the medication in its original container, tightly sealed, to prevent contamination and maintain its integrity. Always be mindful of the expiration date, and if the medication is no longer needed or has expired, proper disposal is essential. Do not dispose of it through household waste or water systems; instead, consult your pharmacist or healthcare professional for guidance on safe disposal practices. Remember to exercise caution and keep the tablets out of the reach of children to prevent accidental consumption.

  • Quick Tips, if any

    Following are the quick tips for Solifenacin Succinate 10mg Tablet:

    • Take the tablet as directed by your doctor; do not crush or chew it.
    • Consume the tablet with water; avoid alcohol while on this medication.
    • Maintain a consistent daily routine for taking the tablet.
    • If you experience dry mouth, increase fluid intake and consider chewing sugar-free gum.
    • Avoid activities requiring mental alertness until you know how the medicine affects you.
    • Inform your doctor about all medications you are taking to prevent potential interactions.
    • Store the tablets at room temperature, away from moisture and light.
  • Laboratory Screening

    Solifenacin Succinate is a medication prescribed to alleviate symptoms of overactive bladder and prostate enlargement. While this medication is not known to require routine lab tests during typical use, it is crucial to consult with a doctor or healthcare provider for individualized guidance on possible lab tests. Depending on your specific condition and symptoms, your doctor may deem it necessary to conduct various investigations. Should your doctor deem lab tests necessary, they may order blood tests to check for any effects on your blood count, glucose levels, or internal bleeding. Additionally, kidney function, liver function, and electrolyte levels may be periodically assessed through kidney function tests, liver function tests, and electrolyte panels. Urinalysis and prostate-specific antigen (PSA) tests for males are also possible investigations. These tests are standard, but it's essential to remember that your doctor will determine the necessary lab work based on your specific health and clinical situation.

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