Stugeron (25mg) 50 Tablets

Cinnarizine's primary mechanism of action is as a calcium channel blocker, particularly in the vestibular system and within the inner ear. It acts by inhibiting the influx of calcium ions into cells, which subsequently reduces the activity of vestibular hair cells and diminishes the excitatory signals transmitted to the brain's vomiting center. This action helps to alleviate symptoms associated with motion sickness and vertigo by suppressing the abnormal firing of neurons in the vestibular system, thereby reducing the sensation of spinning or dizziness. Additionally, cinnarizine's antiemetic effect may be attributed to its ability to block histamine and muscarinic receptors in the brain, further contributing to its therapeutic benefits in managing motion-related disorders.

Cinnarizine 25mg

Antihistamine/Antivertigo

Tablet

The following are the uses of Cinnarizine 25mg Tablet:

• Used for controlling and preventing symptoms of motion sickness such as dizziness, nausea, and vomiting.
• Used to treat and manage symptoms of Meniere's disease, providing relief from vertigo, ringing in the ears, and hearing loss.
• Used for reducing and preventing vertigo and dizziness associated with inner ear disorders.
• Used to improve balance and coordination in patients suffering from vestibular disorders.
• Used to alleviate nausea and vomiting caused by certain types of headaches or migraines.
• Used for managing dizziness and nausea after certain types of surgeries or medical procedures.
• Used to enhance blood circulation in the inner ear, promoting better hearing and balance.

Follow these dosage instructions:

• Take as per doctor's Prescription.
• Take one tablet per day as your doctor suggests.
• Your doctor will determine the treatment length based on your symptom severity.

In the case of an overdose of Cinnarizine 25mg Tablets, it is crucial to act promptly. Symptoms may include severe drowsiness, muscle weakness, and impaired coordination. If you suspect an overdose, seek medical assistance immediately. Quick action can prevent potential complications such as respiratory depression or severe hypotension, which may be life-threatening. Prompt medical intervention is key to managing and mitigating the effects of an overdose.

In the case of a missed dose of Cinnarizine 25mg Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for guidance on how to adjust your dosing schedule to ensure the medication's effectiveness. It is generally best to take the missed dose as soon as possible to maintain consistent medication levels in your body.

To take Cinnarizine 25mg Tablet, swallow the tablet whole with a glass of water, preferably with or after a meal, following the dosage instructions provided by your healthcare professional, and do not crush or chew the tablet.

Following are the conditions when Cinnarizine 25mg Tablet should not be used:

• Avoid if allergic to Cinnarizine or any similar antihistamines.
• Do not use if you have a known history of liver or kidney disease.
• Contraindicated in patients with Parkinson's disease.
• Should not be used in individuals with a history of heart rhythm problems (arrhythmias).
• Not suitable for those with a history of stomach or intestinal bleeding.
• Avoid if you have a blockage in your digestive system (stomach or intestines).
• Do not use if you have a condition called 'pheochromocytoma' (a rare adrenal gland tumor).
• Contraindicated during pregnancy and breastfeeding.
• Not recommended for children under 2 years of age.

The side effects of Cinnarizine 25mg Tablet may include:

• Drowsiness or sedation
• Dry mouth
• Skin rashes or itching
• Gastrointestinal discomfort (nausea, vomiting, stomach pain)
• Weight gain
• Difficulty concentrating
• Blurred vision or visual disturbances
• Muscle weakness

Following are the precautions and warnings for Cinnarizine 25mg Tablet:

• This medication should be avoided by individuals with a known allergy to Cinnarizine or related compounds.
• Patients with a history of liver or kidney disease should use this medicine with caution and under medical supervision, as it may require dosage adjustments.
• Cinnarizine may cause drowsiness and dizziness, so patients should avoid driving, operating heavy machinery, or engaging in activities that require mental alertness until they know how the medication affects them.
• Alcohol consumption should be avoided as it can increase the risk of side effects and drowsiness.
• Not recommended for children under 18 years of age unless prescribed by a doctor.
• Elderly patients may be more sensitive to the side effects, particularly dizziness and drowsiness.
• Consult a doctor before taking this medication if you are pregnant, planning to become pregnant, or breastfeeding.
• If you have a history of Parkinson's disease, epilepsy, or any other neurological disorder, inform your doctor before starting this medication.

Following are the drug interactions for Cinnarizine 25mg Tablet:

• Alcohol may enhance the sedative effects of Cinnarizine, leading to increased drowsiness and impaired coordination.
• It can interact with medications metabolized by CYP2D6 enzymes, such as certain antidepressants (e.g., fluoxetine, paroxetine), potentially increasing their blood levels and side effects.
• Cinnarizine may increase the effects of antihypertensive drugs, resulting in low blood pressure.
• Antihistamines and other sedating medications may have additive sedative effects when used with Cinnarizine.
• It may interact with drugs that affect the central nervous system, including opioids and benzodiazepines, leading to enhanced sedation.
• Cinnarizine can potentially interact with H1-antihistamines, increasing the risk of adverse effects.
• Drugs that prolong the QT interval, such as certain antiarrhythmics and antipsychotics, may have additive effects when used concurrently with Cinnarizine.

Following are the food interactions for Cinnarizine 25mg Tablet:

• Cinnarizine may interact with alcohol, leading to increased drowsiness and dizziness. Avoid or limit alcohol consumption during treatment.
• Grapefruit and grapefruit juice should be avoided as they can interfere with the metabolism of Cinnarizine, potentially increasing its levels in the blood and the risk of side effects.
• High-fat meals can slow down the absorption of Cinnarizine, possibly reducing its effectiveness. It is best to take the medication on an empty stomach or with a light meal.
• Caffeine-rich foods and beverages like coffee, tea, and energy drinks may increase the likelihood of nervousness and tremors when combined with Cinnarizine. Consider reducing caffeine intake.
• Avoid eating large amounts of chocolate, as it contains compounds that can inhibit the action of Cinnarizine, potentially reducing its effectiveness.
• Some dairy products, particularly high-fat dairy, might decrease the absorption of Cinnarizine. Consume dairy in moderation and consult your healthcare provider for guidance.
• Certain herbal supplements, such as St. John's Wort, may affect the metabolism of Cinnarizine. Discuss any herbal remedies with your doctor to prevent potential interactions.
• Always follow the advice of your healthcare provider regarding dietary restrictions or recommendations while taking Cinnarizine.

Cinnarizine 25mg Tablets should be stored in a secure and dry location, preferably in a medicine cabinet or a designated storage area. Keep the tablets in their original container, tightly sealed, to maintain their integrity and prevent exposure to moisture or humidity. Avoid storing them in the bathroom or kitchen, as these areas can be prone to temperature fluctuations and moisture. Ensure the tablets are kept away from direct sunlight, as it can degrade the medication. Regularly check the expiration date, and dispose of any expired or unused tablets responsibly. Do not flush them down the toilet or pour them into drains; instead, follow local guidelines for pharmaceutical waste disposal. Keep the medication out of children's reach to prevent accidental consumption.

No

Following are the quick tips for Cinnarizine 25mg Tablet:

• Take the tablet as directed by your doctor; do not exceed the prescribed dosage.
• Swallow the tablet whole with a glass of water; do not crush or chew.
• Maintain a consistent schedule for taking the medication for best results.
• Avoid consuming alcohol while using this medication as it may increase side effects.
• If you experience dizziness, avoid driving or operating heavy machinery.
• Store the medication in a cool, dry place, away from direct sunlight.
• Consult your doctor if you have any pre-existing medical conditions or are taking other medications.