Tamiso MR (0.4mg) 10 Capsules

Tamsulosin 4mg capsules primarily exert their therapeutic effect through selective blockade of alpha-1A and alpha-1D adrenoceptors located in the prostate and bladder neck. By inhibiting these receptors, tamsulosin relaxes smooth muscle tissue, leading to improved urine flow and reduced symptoms associated with benign prostatic hyperplasia (BPH). This selective action helps to minimize unwanted cardiovascular side effects, as tamsulosin has a higher affinity for alpha-1A and alpha-1D receptors compared to alpha-1B receptors found in the vasculature. The relaxation of smooth muscle in the prostate and bladder neck facilitates easier urination and alleviates the symptoms of BPH, such as urinary hesitancy, weak stream, and incomplete bladder emptying.

Alpha-blocker.

Capsule

The following are the uses of Tamsulosin 4mg Capsule:

• Used for relieving symptoms of an enlarged prostate, such as difficulty in urination.
• Used for treating painful urination and urinary urgency.
• Used to improve urine flow and reduce bladder outlet obstruction.
• Used for treating benign prostatic hyperplasia (BPH), providing symptom relief.
• Used to help patients with lower urinary tract symptoms associated with BPH.
• Used to promote relaxation of the prostate and bladder neck muscles.
• Used to prevent and manage acute urinary retention in BPH patients.

To be used as per doctor's instructions

In the case of an overdose of Tamsulosin 4mg Capsules, individuals may experience a range of symptoms, including a significant drop in blood pressure, leading to dizziness and fainting. Other potential effects include a rapid or irregular heartbeat, difficulty breathing, and severe headaches. It is important to promptly seek medical assistance if an overdose is suspected, as healthcare professionals can provide appropriate treatment to manage these symptoms and ensure the individual's well-being.

In the case of a missed dose of Tamsulosin 4mg Capsule, it is important to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for guidance on how to adjust your dosage and get back on track with your treatment plan.

To take Tamsulosin 4mg Capsule, swallow the capsule whole with a full glass of water, preferably at the same time each day, following the dosage instructions provided by your healthcare provider.

Following are the conditions/situations when Tamsulosin 4mg Capsule should not be used:

• Avoid using if you have a known allergy to Tamsulosin or other similar medications.
• Do not take this medication if you have a history of severe liver problems.
• Contraindicated in individuals with a condition called hypotension (low blood pressure).
• Should not be used if you have a history of fainting spells or dizziness upon standing up.
• Not suitable for individuals with a rare eye condition called 'narrow-angle glaucoma'.
• Do not use this medication if you have recently had eye surgery or plan to have eye surgery.
• Avoid using Tamsulosin if you have severe kidney problems or are on dialysis.

The side effects of Tamsulosin 4mg Capsule may include:

• Dizziness or lightheadedness
• Headache
• Fatigue or weakness
• Nausea and vomiting
• Diarrhea or constipation
• Skin rash or itching
• Insomnia (difficulty sleeping)
• Nasal congestion or runny nose

Following are the precautions and warnings for Tamsulosin 4mg Capsule:

• Not recommended for individuals with known allergies to Tamsulosin or other similar medications.
• Patients with a history of orthostatic hypotension should exercise caution, as Tamsulosin may cause a sudden drop in blood pressure upon standing.
• Requires careful administration in patients with severe renal impairment, and regular monitoring of kidney function is advised.
• May cause dizziness or drowsiness; patients should avoid activities requiring alertness until they know how the medication affects them.
• Not suitable for individuals with severe liver impairment, as Tamsulosin is extensively metabolized in the liver.
• Should be used with caution in elderly patients, starting with a lower dose and gradually adjusting as needed.
• Patients with a history of eye problems, especially narrow-angle glaucoma, should be monitored closely during treatment.
• Not recommended for children, as the safety and efficacy of Tamsulosin in the pediatric population have not been established.

Following are the drug interactions for Tamsulosin 4mg Capsule:

• May interact with phosphodiesterase-5 (PDE-5) inhibitors like sildenafil, tadalafil, or vardenafil, leading to hypotension and orthostatic hypotension.
• Alpha-blockers such as prazosin or doxazosin can enhance the blood pressure-lowering effect of Tamsulosin, potentially causing excessive hypotension.
• Drugs metabolized by the CYP3A4 enzyme, including some antifungals (ketoconazole) and antibiotics (erythromycin), may increase Tamsulosin levels, leading to increased side effects.
• Antihypertensive medications like beta-blockers or diuretics can have additive effects with Tamsulosin, potentially causing excessive blood pressure reduction.
• Tricyclic antidepressants and antipsychotics may interact with Tamsulosin, affecting its metabolism and potentially increasing side effects.
• Caution is advised with medications that can cause orthostatic hypotension, such as certain antipsychotics or antidepressants, as Tamsulosin may enhance this effect.
• Tamsulosin may increase the effects of antihypertensive drugs, requiring close monitoring of blood pressure.

Following are the food interactions for Tamsulosin 4mg Capsule:

• Grapefruit and grapefruit juice consumption should be avoided as they can lead to increased blood levels of Tamsulosin, potentially causing a drop in blood pressure and an increased heart rate.
• Alcohol intake should be limited as it may exacerbate side effects such as dizziness and fainting, especially when standing up from a sitting or lying position.
• Avoid high-fat meals as they may decrease the absorption of Tamsulosin, reducing its effectiveness.
• Consuming foods rich in potassium like bananas, oranges, and spinach is important as Tamsulosin can sometimes cause potassium levels to drop.
• Salt substitutes containing potassium should be used cautiously as Tamsulosin may also increase potassium levels, and excessive potassium can be harmful.
• Stay well-hydrated by drinking plenty of fluids, especially water, to maintain overall health and support the medication's effectiveness.
• Avoid large meals before bedtime as Tamsulosin can cause dizziness and fainting, and eating late may disrupt sleep.
• Inform your healthcare provider about any dietary changes or if you have any specific food preferences to ensure the medication's safe and effective use.

Tamsulosin 4mg capsules should be stored in a cool and dry place, preferably at room temperature, ensuring protection from direct exposure to sunlight and moisture. The original packaging should be tightly sealed to maintain the integrity of the medication. It is crucial not to store the capsules in areas like the bathroom or near heating appliances, as temperature fluctuations can compromise their effectiveness. Always check the expiration date before use, and for disposal, do not flush or pour the medication down the drain. Instead, consult a pharmacist or healthcare professional for appropriate disposal methods to ensure environmental safety. Keep the medication away from children to prevent accidental consumption.

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Following are the quick tips for Tamsulosin 4mg Capsule:

• Take the capsule as directed by your doctor, usually once daily, preferably after the same meal each day.
• Swallow the capsule whole with a full glass of water; do not crush, chew, or open it.
• Stand or sit upright for at least 30 minutes after taking the capsule to prevent irritation to your throat.
• Avoid taking antacids or mineral supplements containing aluminum, magnesium, or calcium within 2 hours of taking this medication.
• Inform your doctor if you have any allergies or medical conditions before starting this medication.
• Store the capsules at room temperature, away from moisture and light.
• Regularly monitor your blood pressure and heart rate while taking this medication and report any unusual changes to your doctor.