Telsarta-D (40/12.5mg) 14 Tablets

Telmisartan and Hydrochlorothiazide are the two active components in the Telmisartan 40mg, Hydrochlorothiazide 12.5mg Tablet. Telmisartan is an angiotensin II receptor blocker (ARB) that prevents the binding of angiotensin II to its receptors, primarily in the vascular smooth muscle and adrenal glands. By blocking the effects of angiotensin II, telmisartan causes vasodilation, reduces blood pressure, and decreases aldosterone secretion, leading to reduced fluid retention. Hydrochlorothiazide, on the other hand, is a diuretic that inhibits the reabsorption of sodium and chloride ions in the distal convoluted tubule of the kidney, promoting the excretion of water and electrolytes, which contributes to a decrease in blood volume and blood pressure. Together, these mechanisms result in a synergistic antihypertensive effect, making the combination effective in treating hypertension.

Angiotensin II receptor blocker, thiazide diuretic.

Tablet

The following are the uses of Telmisartan 40mg, Hydrochlorothiazide 12.5mg Tablet:

• Used for managing high blood pressure, effectively lowering it to healthy levels.
• Used for treating hypertension to reduce the risk of heart disease and stroke.
• Used for controlling blood pressure in patients with diabetes or kidney issues.
• Used for reducing excess fluid and salt retention, addressing hypertension-related edema.
• Used for improving overall cardiovascular health and blood vessel flexibility.
• Used for preventing potential complications from uncontrolled hypertension.
• Used for long-term management of blood pressure with regular monitoring.

To be taken as per doctor's prescription

In the case of an overdose of Telmisartan 40mg and Hydrochlorothiazide 12.5mg tablets, symptoms may include excessive dizziness, severe dehydration, and a significant drop in blood pressure. Patients may experience increased urination, weakness, and an irregular heartbeat. It is important to seek medical advice promptly, as treatment may involve supportive care and close monitoring of vital signs to prevent further complications. Timely intervention can help manage the adverse effects and ensure the patient's well-being.

In the case of a missed dose of Telmisartan 40mg and Hydrochlorothiazide 12.5mg Tablet, it is advisable to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss several doses, consult your healthcare professional for advice on how to safely resume your medication without affecting its efficacy.

To take the Telmisartan 40mg, Hydrochlorothiazide 12.5mg Tablet, swallow the tablet whole with a glass of water, preferably at the same time each day, as directed by your healthcare provider.

Following are the conditions or situations when Telmisartan 40mg, Hydrochlorothiazide 12.5mg Tablet should not be taken:

• Should not be used in patients with a known allergy to Telmisartan, Hydrochlorothiazide, or any other angiotensin II receptor blockers (ARBs).
• Contraindicated in individuals with a history of severe liver impairment or liver disease.
• Not recommended for patients with severe kidney disease or those on dialysis.
• Should not be used in individuals with low blood potassium levels (hypokalemia) or low blood sodium levels (hyponatremia).
• Contraindicated during pregnancy, especially in the second and third trimesters.
• Should be avoided in patients with a history of angioedema (swelling of the face, lips, throat, or tongue) associated with previous use of similar medications.
• Not suitable for individuals with severe dehydration or those who are unable to produce adequate urine output.

The side effects of Telmisartan 40mg, Hydrochlorothiazide 12.5mg Tablet may include:

• Dizziness or lightheadedness
• Fatigue or weakness
• Nausea and vomiting
• Diarrhea or constipation
• Dry mouth
• Skin rash or itching
• Muscle cramps
• Increased sensitivity to sunlight

Following are the precautions and warnings for Telmisartan 40mg, Hydrochlorothiazide 12.5mg Tablet:

• Individuals with a known allergy to Telmisartan, Hydrochlorothiazide, or any other ingredients in the tablet should not consume this medication.
• Patients with a history of kidney or liver problems should exercise caution and inform their healthcare provider, as dosage adjustments might be necessary.
• It is important to maintain proper hydration while taking this medication, especially in hot weather or during exercise, to prevent excessive fluid loss.
• Regular monitoring of blood pressure, kidney function, and electrolyte levels is recommended during treatment.
• Patients with diabetes should be cautious as Hydrochlorothiazide may alter blood sugar levels.
• This medication may cause dizziness or lightheadedness, especially when standing up suddenly, so caution is advised when performing tasks that require alertness.
• Pregnant or breastfeeding women should consult their doctor before taking this medication, as it may not be suitable during these periods.
• Elderly patients may be more susceptible to side effects, and dosage adjustments might be required.

Following are the drug interactions for Telmisartan 40mg, Hydrochlorothiazide 12.5mg Tablet:

• Telmisartan may increase the risk of hyperkalemia (high potassium levels) when taken with potassium-sparing diuretics, potassium supplements, or salt substitutes. Blood potassium levels should be monitored regularly.
• Hydrochlorothiazide may decrease the effectiveness of medications like lithium, increasing the risk of lithium toxicity. Close monitoring of lithium levels is recommended.
• The combination of Telmisartan with other antihypertensive medications (e.g., ACE inhibitors, beta-blockers, calcium channel blockers) may lead to excessive blood pressure lowering, causing hypotension. Blood pressure should be monitored regularly.
• Concurrent use of Telmisartan with nonsteroidal anti-inflammatory drugs (NSAIDs) (e.g., ibuprofen, naproxen) can reduce the antihypertensive effect and increase the risk of kidney impairment. Kidney function should be monitored.
• Hydrochlorothiazide may interact with other medications that lower blood sugar (e.g., insulin, sulfonylureas), leading to an increased risk of hypoglycemia. Blood glucose levels should be monitored in diabetic patients.
• Telmisartan and Hydrochlorothiazide may cause dehydration, which can be exacerbated by the use of other diuretics or agents that lower blood volume. Caution should be exercised when used with such medications.
• Co-administration with corticosteroids or other medications that affect electrolytes (e.g., corticosteroids, amphotericin B) may increase the risk of electrolyte imbalances (e.g., hypokalemia).
• The combination may increase the risk of renal impairment when used with other nephrotoxic drugs (e.g., certain antibiotics, NSAIDs). Kidney function should be regularly monitored.
• Taking Telmisartan with alcohol can increase the risk of low blood pressure and dizziness. It is recommended to limit alcohol consumption during treatment.

Following are the food interactions for Telmisartan 40mg, Hydrochlorothiazide 12.5mg Tablet:

• Grapefruit and grapefruit juice should be consumed with caution as they may increase the levels of Telmisartan, affecting blood pressure control.
• Avoid excessive alcohol intake as it may increase the risk of dizziness and affect blood pressure.
• Maintain a consistent potassium-rich diet, as Hydrochlorothiazide can cause potassium loss. Include foods like bananas, oranges, and spinach.
• Salt substitutes containing potassium should be used cautiously to prevent high potassium levels.
• Avoid licorice, especially if you have heart issues, as it may interfere with Telmisartan's effects.
• Stay hydrated, and consume a balanced diet to support overall health while on this medication.
• No significant food interactions impact the absorption of these medications, but consult your doctor for personalized advice.

Telmisartan 40mg, Hydrochlorothiazide 12.5mg Tablets should be stored in a cool and dry place, preferably at room temperature, ensuring protection from light and moisture. The tablets should be kept in their original packaging, tightly sealed, to maintain their integrity and effectiveness. It is crucial to adhere to the recommended storage conditions to preserve the medication's quality. When disposing of unused or expired tablets, avoid flushing them down the toilet or discarding them into drains. Instead, consult a pharmacist or healthcare professional for appropriate disposal methods to minimize environmental impact. Keep the medication away from children to prevent accidental consumption.

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Following are the quick tips for Telmisartan 40mg, Hydrochlorothiazide 12.5mg Tablet:

• Consult your doctor for the right dosage and duration of this medication.
• Take the tablet as directed, usually once daily with or without food.
• Ensure you stay well-hydrated while taking this medication.
• If you miss a dose, take it as soon as you remember, unless it's almost time for the next dose.
• Do not double the dose to make up for a missed one.
• Inform your doctor about all the medications you are currently taking to avoid potential interactions.
• Store the tablets in a cool, dry place, away from direct sunlight and moisture.