Thyroxine Tab (Global Pharma) 100's

Thyroxine Tablet, which contains the active ingredient levothyroxine, is a synthetic form of the thyroid hormone thyroxine (T4). Its mechanism of action is centered on replacing or supplementing the body's natural thyroid hormone production. When administered, levothyroxine mimics the actions of endogenous thyroid hormones, primarily thyroxine (T4) and its active metabolite triiodothyronine (T3). These hormones bind to thyroid hormone receptors in the cell nucleus, regulating gene expression and influencing various physiological processes. The primary effect is to increase the basal metabolic rate by enhancing the body's oxygen and energy consumption. This leads to increased heat production, protein synthesis, and enzymatic activity, ultimately affecting nearly every physiological system in the body, including cardiovascular, digestive, and nervous systems. By providing sufficient thyroid hormone, Thyroxine Tablet helps maintain normal metabolic and physiological functions, particularly in individuals with hypothyroidism.

Thyroxine:

Tablet

The following are the uses of Thyroxine Tablet:

• Used for treating hypothyroidism, a condition where the thyroid gland doesn't produce enough thyroid hormones.
• Used to manage an underactive thyroid, helping to regulate metabolism and body functions.
• Effective in relieving symptoms like fatigue, weight gain, and sensitivity to cold.
• Can be used to improve energy levels and overall well-being in patients with thyroid hormone deficiency.
• Helps in maintaining healthy hair, skin, and nails, which can be affected by thyroid imbalances.
• Aids in cognitive function and mood regulation, addressing issues like brain fog and depression associated with hypothyroidism.
• Used to support fertility and pregnancy in women with thyroid disorders, ensuring proper fetal development.
• May also be utilized to prevent goiter (enlarged thyroid gland) and its complications.

In the case of an overdose of Thyroxine Tablets, individuals may experience symptoms such as rapid heartbeat, chest pain, confusion, and seizures. If an overdose is suspected, it is crucial to seek medical advice promptly. The healthcare provider may recommend immediate treatment options, including observation, supportive care, and managing the symptoms until the excess medication is cleared from the body. Prompt action can help mitigate the risks associated with Thyroxine Tablet overdoses.

In the case of a missed dose of Thyroxine Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one. If you miss several doses, consult your healthcare professional for advice, as they may recommend adjusting your dosage or provide specific instructions to ensure you receive the correct amount of medication.

To take the Thyroxine Tablet, swallow the tablet whole with a full glass of water on an empty stomach, preferably first thing in the morning, at least 30 minutes before eating breakfast, following the dosage instructions provided by your healthcare professional.

The following conditions or situations are contraindications for the use of Thyroxine Tablet:

• Allergy or hypersensitivity to Thyroxine or any of its ingredients.
• Patients with an untreated or uncontrolled adrenal gland disorder, as it may lead to adrenal crisis.
• Individuals with untreated thyrotoxicosis (excess thyroid hormone in the body).
• Recent history of heart attack or unstable angoric heart disease.
• Uncorrected thyrotoxicosis caused by over-replacement with thyroid hormone.
• Thyroid hormone replacement in patients with subclinical hypothyroidism or isolated thyroid hormone abnormalities.
• Patients with a history of pituitary gland suppression due to thyroid hormone therapy.
• Use with caution in patients with diabetes as it may affect blood sugar control.

The side effects of Thyroxine Tablet may include:

• Weight loss
• Increased appetite
• Restlessness or tremors
• Diarrhea
• Sweating
• Sensitivity to heat
• Hair loss
• Palpitations or rapid heartbeat

Following are the precautions and warnings for Thyroxine Tablet:

• This medication should be used with caution in patients with a history of cardiovascular disease, as it may impact heart rate and blood pressure.
• Regular monitoring of thyroid function tests is necessary, and dosage adjustments should be made based on these results.
• Patients with diabetes should closely monitor their blood sugar levels as Thyroxine can affect glucose metabolism.
• Elderly individuals may be more sensitive to the effects, so starting with a lower dose is recommended.
• Do not abruptly stop taking the tablet without consulting your doctor, as it may lead to withdrawal symptoms.
• Inform your doctor about all medications you are currently taking to avoid potential drug interactions.
• Pregnant and breastfeeding women should use Thyroxine only if clearly needed and under medical supervision.

Following are the drug interactions for Thyroxine Tablet:

• Concomitant use with antacids containing aluminum or calcium, or iron supplements, can reduce the absorption of Thyroxine, leading to decreased effectiveness.
• Taking Thyroxine with certain antidepressants like tricyclic antidepressants or selective serotonin reuptake inhibitors (SSRIs) may require dosage adjustments of both medications.
• It may decrease the effectiveness of blood thinners (e.g., warfarin) or increase the risk of bleeding when used concurrently.
• Thyroxine can alter the effects of diabetes medications, including insulin and oral hypoglycemic agents, requiring careful monitoring of blood sugar levels.
• When combined with estrogen-containing medications, such as oral contraceptives or hormone replacement therapy, Thyroxine dosage adjustments may be necessary.
• The use of Thyroxine with sympathomimetic drugs (e.g., epinephrine, beta-blockers) may enhance the effects of these medications on the cardiovascular system.
• Caution is advised when taking Thyroxine with drugs that affect liver metabolism, as it may change the drug's effectiveness.

Following are the food interactions for Thyroxine Tablet:

• Avoid excessive consumption of iodine-rich foods like seaweed, kelp, or iodine-fortified foods as they may affect thyroid function.
• Soy-based products like tofu, soy milk, and edamame can interfere with the absorption of Thyroxine, so it's best to separate soy intake from medication by several hours.
• High-fiber foods such as bran cereals, whole grains, and legumes can reduce the absorption of Thyroxine. Consume these foods at a different time than your medication.
• Calcium-rich foods like dairy products, calcium-fortified juices, and supplements can also interfere with absorption. Avoid taking Thyroxine with calcium-rich foods or supplements.
• Coffee and tea may decrease the absorption of Thyroxine. It is advisable to limit or avoid these beverages around the time of medication intake.
• Iron supplements and iron-rich foods like red meat and spinach can also impact absorption. Take iron supplements at a different time than Thyroxine, preferably several hours apart.
• Certain vegetables like broccoli, cabbage, and Brussels sprouts contain goitrogens, which can affect thyroid function. Cooking these vegetables can reduce the effect, but it's best to consume them in moderation.

Thyroxine Tablets should be stored in a cool and dry place, preferably at room temperature (around 20-25°C). Keep the tablets in their original container, tightly sealed, to protect them from moisture and light. Avoid storing them in the bathroom or kitchen, as these areas may have temperature fluctuations and humidity. Do not refrigerate or freeze the tablets. Always check the expiration date, and dispose of any expired or unused tablets responsibly. When disposing of medication, do not throw it in the trash or flush it down the toilet; instead, consult your pharmacist or local waste management guidelines for safe disposal methods. Keep the medication out of children's reach to prevent accidental consumption.

Following are the quick tips for Thyroxine Tablet:

• Take the tablet on an empty stomach, preferably 30 minutes before breakfast, for optimal absorption.
• Swallow the tablet whole with a full glass of water, ensuring not to crush or chew it.
• Maintain a consistent daily routine by taking the tablet at the same time each day.
• Avoid consuming food or beverages containing soy, iron, calcium, or fiber immediately after taking the tablet.
• Wait at least 4 hours after taking the tablet before consuming products containing these substances.
• Regularly monitor your thyroid function through blood tests as advised by your doctor.
• Store the tablets at room temperature, away from light and moisture, to maintain their effectiveness.