Urigo (80mg) 20 Tablets

Febuxostat is a unique drug in that it is a non-purine inhibitor of xanthine oxidase, the enzyme responsible for breaking down hypoxanthine and xanthine, which ultimately inhibits the production of uric acid. This medication is absorbed from the gastrointestinal tract with a median Tmax of 1.5 hours, though food has a minimal effect on the drug's oral bioavailability. Febuxostat's mechanism of action makes it a useful tool for treating gout, a common type of arthritis whose symptoms include joint swelling, pain, and inflammation. Interestingly, febuxostat also decreases the risk of gout flares. These factors make febuxostat a viable option for patients suffering from hyperuricemia and gout. This medication is provided as Febuxostat 80mg, which represents the drug's strength. It is essential to read the medication information sheet and instructions for use provided with this medicine before starting treatment. Talking to your doctor or pharmacist is necessary if you have any questions. Ultimately, your doctor will provide individualized guidance about when and how to take the medication, tailoring the dose to your specific condition and current treatments. It is vital that you do not miss any doses for the drug to work effectively. It is important to tell your doctor about all the medications you are currently taking before starting Febuxostat, including over-the-counter medications, vitamins, and supplements. Additionally, inform your doctor if you have any allergies to any medications. This medication should not be discontinued abruptly without consulting the doctor. It should be used only when prescribed during pregnancy and breastfeeding, and informed consent should be taken from the patient/guardian before the therapy initiation.

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Xanthine Oxidase Inhibitor

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Tablet

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Unveiling its multifaceted uses and transformative applications as follows:

• Febuxostat is used to treat gout attacks and maintain uric acid levels in adults with gout
• Used to decrease uric acid levels in adults with cancer or tumor of the kidneys (leukemias, lymphomas, and other cancers)
• Febuxostat helps to decrease uric acid levels in the body, reducing the risk of gout flares

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Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• Gout- Take 80 mg once a day in the morning to relieve gout symptoms.
• Kidney Stones- Take 80 mg once a day in the morning to prevent the formation of kidney stones.

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In case of an overdose of febuxostat, seek immediate medical attention. Symptoms may include dizziness, nausea, vomiting, headache, or abnormal liver function. Treatment typically involves supportive care, including monitoring vital signs and managing any symptoms that arise. It is important to bring the medication packaging or any information about the dosage taken to assist healthcare providers in determining the appropriate course of action. 

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If you miss a dose of Febuxostat 80mg, it is important to determine the best course of action to ensure your safety and optimize the medication's effectiveness. You may take the missed dose as soon as you remember it, but if it is almost time for the next dose, it is recommended to skip the missed dose and continue with your regular dosage schedule. Doubling the dose to catch up should be avoided, as it may lead to an overdose or adverse effects. To maintain the drug's effectiveness in managing your condition, it is essential to adhere to the prescribed dosing schedule as closely as possible. If you have any further questions or concerns about missing a dose, it is always advisable to consult with your doctor or seek professional help to ensure the best outcome for your specific situation.

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Before you take Febuxostat, ensure you read the medication guide given by your doctor or pharmacist. Also, reading the warning label on the packaging is important. Make sure not to take more or less of the medication than what is prescribed, and use it for the full course of treatment. Febuxostat is taken once daily, with or without food, and it is best to take it at the same time each day. Swallow the tablet whole without crushing or chewing it, as this affects the release of the medication and its effects. If you experience challenges swallowing the tablet, you can ask your doctor or pharmacist for advice. It is essential to keep taking this medication even if you feel well, as it is used to prevent gout attacks. If you have concerns while taking Febuxostat, contact your doctor or pharmacist immediately. They may advise you to adjust the dosage or give you additional instructions. Inform your doctor about all the medications you are currently taking, including vitamins and herbal supplements, as Febuxostat may interact with certain drugs. If you miss a dose, take it as soon as possible. However, if it is closer to the time for the next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.Store this medication in a cool, dry place away from direct heat or light. Keep it in a container with a child-proof cap, out of the reach of children and pets.

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Discerning instances where this medication may not be appropriate:

• Febuxostat is a medication that is taken once daily at a dose of 80 mg to regulate uric acid levels in people with gout.
• Do not take Febuxostat 80mg if you are taking other medications that affect uric acid levels, have a known allergy or hypersensitivity to Febuxostat or any medication, have certain blood disorders, kidney problems, liver disease, a history of cancer, are pregnant or planning to become pregnant, or are breastfeeding.
• Taking Febuxostat 80mg under these circumstances may lead to excessive lowering of uric acid levels, allergy symptoms, harm to the foetus during pregnancy, and the potential to pass into breast milk and harm the baby.

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Unraveling the side effects lurking behind this medications are as follows:

• Febuxostat cause a decrease in hemoglobin, leading to fatigue and dizziness.
• It can cause a decrease in platelet count, leading to easy bleeding and bruising.
• Febuxostat may cause kidney failure and is not suitable for those with existing kidney conditions.
• It may also cause liver failure and is not suitable for those with existing liver conditions.
• High blood potassium levels may occur, leading to abnormal heart rhythm and kidney failure.

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Patients should be aware of these precautions and warnings when considering the use of febuxostat:

• Avoid febuxostat if you have a history of hypersensitivity reactions to allopurinol.
• It is not recommended for individuals with major cardiovascular diseases, such as myocardial infarction, stroke, or unstable angina, or those with thyroid disorders.
• Use with caution in patients at increased risk for urate formation, including those with Lesch-Nyhan syndrome, malignant diseases, or undergoing related treatments.
• Organ transplant recipients should also be cautious when using febuxostat.
• Do not start febuxostat during an acute gout attack.
• It should be used primarily for patients who are intolerant to allopurinol or for whom allopurinol is contraindicated or ineffective.
• Avoid use for asymptomatic or secondary hyperuricemia.
• Patients with hepatic or renal impairment, as well as those who are pregnant or breastfeeding, should avoid using febuxostat.

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Drug interactions with febuxostat include:

• Theophylline (may increase theophylline levels- monitor for theophylline toxicity)
• Azathioprine (may increase azathioprine levels- monitor for increased toxicity)
• Mercaptopurine (may increase mercaptopurine levels- monitor for increased toxicity)
• Warfarin (may increase bleeding risk- monitor INR closely)
• Cyclosporine (may increase cyclosporine levels- monitor for increased side effects)
• Diuretics (e.g., furosemide) (may increase the risk of renal impairment- monitor renal function)
• Colchicine (may increase colchicine levels- monitor for colchicine toxicity)
• Antacids (e.g., magnesium hydroxide) (may decrease febuxostat absorption- take febuxostat at least 2 hours before antacids)
• Alcohol (may affect uric acid levels-monitor uric acid levels)

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Febuxostat is a specialized medication used to treat gout. It is essential to follow the guidance of your prescribing physician or pharmacist for proper storage of the medication to ensure its effectiveness and safety. febuxostat should be stored at room temperature, ideally at 77°F (25°C). Keep the medication in an opaque container to keep out light, and avoid heat and moisture. It is important to keep febuxostat out of the reach of children and pets. Note that storage instructions may vary, so it is critical to refer to the medication's specific instructions provided by the pharmacist or physician. If you have any questions or concerns about storing febuxostat, ask your doctor or pharmacist for guidance.

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Febuxostat is a medication that requires laboratory tests to identify its side effects. The tests required may differ from person to person, but here are some suggested tests that may be necessary if you are taking Febuxostat 80mg. Firstly, kidney function tests may be needed as Febuxostat can cause kidney damage to those with pre-existing kidney problems. These tests include serum creatinine, creatinine clearance, and estimated glomerular filtration rate (eGFR) to determine kidney function. Secondly, liver function tests may be required, albeit rarely, to catch any early signs of liver injury. These liver enzymes include alanine aminotransferase (ALT) and aspartate aminotransferase (AST), as well as bilirubin levels. Thirdly, Blood Urea Nitrogen (BUN) and Sodium Levels are suggested as BUN levels may rise in cases of acute kidney injury, a possible complication of Febuxostat treatment. Monitoring these levels can evaluate kidney function and identify early signs of kidney problems. A Complete Blood Count (CBC) may be performed to monitor any blood cell count abnormalities like anemia (low red blood cells), leukopenia (low white blood cells), or thrombocytopenia (low platelet count). Febuxostat may rarely cause agranulocytosis, which is characterized by very low white blood cell counts. Finally, a Lipid Profile may be necessary to monitor lipid levels like cholesterol and triglycerides as Febuxostat may cause changes in lipids, especially for those with a history of cardiovascular disease or elevated lipids. It is vital to follow medical professional recommendations for individual cases and speak with a doctor about which laboratory tests are suitable for you.

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