Vadil (3.125mg) 30 Tablets

Carvedilol 12.5mg Tablet primarily acts as a non-selective beta-blocker and alpha-1 adrenergic receptor antagonist. Its mechanism of action involves blocking beta-adrenergic receptors in the heart and peripheral vasculature, leading to decreased cardiac output and reduced peripheral vascular resistance. By blocking beta-1 receptors, carvedilol decreases heart rate and myocardial contractility, resulting in reduced cardiac workload and oxygen demand. Simultaneously, its blockade of alpha-1 receptors causes vasodilation, which lowers blood pressure by decreasing peripheral vascular resistance. This dual action contributes to the medication's effectiveness in managing hypertension and congestive heart failure, as it improves blood flow, reduces cardiac stress, and helps maintain a stable cardiovascular system.

Carvedilol 12.5mg

Beta-blocker, Alpha-blocker

Tablet

The following are the uses of Carvedilol 12.5mg Tablet:

• Used for managing hypertension, effectively lowering high blood pressure.
• Used to treat heart failure, improving heart function and reducing symptoms.
• Used to reduce the risk of death after a heart attack, aiding in recovery.
• Used to alleviate angina symptoms, reducing chest pain and discomfort.
• Used to manage irregular heart rhythms, helping restore a normal heartbeat.
• Used to lower blood pressure in patients with kidney disease and hypertension.
• Used to enhance exercise capacity in patients with cardiovascular issues.

Follow these dosage instructions:

• Adult Dosage

20 milligrams (mg) once a day for 7 to 14 days. Your doctor may adjust your dose as needed. However, the dose is usually not more than 80 mg once a day.

• Child Dosage

The dosage for the child is strictly recommended by the doctor.

In the case of an overdose of Carvedilol 12.5mg tablets, it is important to recognize the potential severity of the situation. Symptoms may include dizziness, extreme fatigue, and a significantly slow heart rate. If an overdose is suspected, immediate medical advice should be sought. Prompt action can ensure appropriate treatment and management of any adverse effects, potentially preventing serious health complications. Timely intervention is key to addressing such situations effectively.

In the case of a missed dose of Carvedilol 12.5mg Tablet, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, it is best to skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, consult your healthcare provider for guidance on how to safely resume your medication regimen. It's important to maintain a consistent dosing routine for the medication to be most effective.

To take Carvedilol 12.5mg Tablet, swallow the tablet whole with a glass of water, preferably at the same time each day, following the dosage instructions provided by your healthcare provider.

Following are the conditions when Carvedilol 12.5mg Tablet should not be used:

• Should not be taken if you are allergic to Carvedilol or any similar medications.
• Contraindicated in patients with severe liver problems or liver failure.
• Not suitable for individuals with severe heart conditions, such as heart block, sick sinus syndrome, or severe heart failure.
• Should not be used if you have a history of slow heart rate (bradycardia) or conditions that cause prolonged pauses in your heart rhythm.
• Avoid if you have asthma or chronic obstructive pulmonary disease (COPD) that is currently causing breathing problems.
• Do not use if you have a condition called cardiogenic shock, where your heart cannot pump enough blood to meet your body's needs.
• Should not be taken if you have untreated pheochromocytoma, a rare tumor of the adrenal gland.

The side effects of Carvedilol 12.5mg Tablet may include:

• Dizziness
• Fatigue or weakness
• Diarrhea
• Nausea
• Shortness of breath
• Slow heart rate
• Swelling in the hands and feet
• Weight gain

Following are the precautions and warnings for Carvedilol 12.5mg Tablet:

• Patients with a known allergy to Carvedilol or similar medications should not take this medicine.
• This medication can cause dizziness and lightheadedness, especially when starting treatment or increasing the dose. Avoid driving, operating heavy machinery, or engaging in activities that require alertness until you know how this medicine affects you.
• Carvedilol can mask the symptoms of low blood sugar, especially in individuals with diabetes. Monitor blood sugar levels regularly and be cautious of hypoglycemic symptoms.
• It may cause a decrease in blood pressure, especially in patients with cardiovascular conditions. Regular monitoring of blood pressure is necessary, and adjustments may be required.
• Patients with a history of liver or kidney disease should exercise caution and inform their healthcare provider, as the dose may need to be adjusted.
• Elderly patients may be more sensitive to the effects of Carvedilol, particularly related to blood pressure and heart rate. Close monitoring is advised.
• If you have a history of severe heart problems, bronchial asthma, or chronic obstructive pulmonary disease (COPD), consult your doctor as Carvedilol may not be suitable for you.
• Always inform your healthcare provider about all the medications you are currently taking to avoid potential drug interactions.

Following are the drug interactions for Carvedilol 12.5mg Tablet:

• Carvedilol can interact with calcium channel blockers (e.g., verapamil, diltiazem), leading to increased risk of bradycardia and heart block.
• Concomitant use with clonidine may result in increased risk of hypotension and bradycardia; abrupt discontinuation of either drug may lead to severe hypertension.
• It may enhance the effects of hypoglycemic agents, including insulin, and increase the risk of hypoglycemia.
• The effects of carvedilol and digoxin may be additive, leading to prolonged heart rate reduction.
• Rifampicin can decrease the effectiveness of carvedilol by inducing its metabolism.
• The use of carvedilol with general anesthetics may result in prolonged hypotension and bradycardia.
• Caution is advised when combining with other medications that block alpha-adrenergic receptors, as this may cause hypotension.

Following are the food interactions for Carvedilol 12.5mg Tablet:

• Grapefruit and grapefruit juice consumption should be avoided as they can increase Carvedilol levels in the blood, potentially leading to increased side effects, especially those related to the heart.
• Alcohol intake is not recommended as it can increase the risk of low blood pressure and may also enhance the sedative effects of Carvedilol, causing dizziness and drowsiness.
• Caffeinated beverages like coffee or energy drinks should be limited as they can counteract the blood pressure-lowering effect of Carvedilol.
• High-sodium foods should be minimized as Carvedilol is often prescribed to manage blood pressure, and excessive sodium can counteract its effectiveness.
• A balanced diet rich in fruits, vegetables, whole grains, and lean proteins is generally recommended to support overall cardiovascular health while taking Carvedilol.
• Avoid excessive consumption of foods rich in tyramine, such as aged cheeses, cured meats, and certain types of beer, as they can interact with Carvedilol and lead to a sudden increase in blood pressure.
• Always consult your healthcare provider for specific dietary recommendations based on your health condition and medication regimen.

Carvedilol 12.5mg Tablets should be stored in a cool and dry place, preferably at room temperature, away from direct exposure to sunlight, moisture, and heat. The original container should be used to keep the tablets protected from external factors and to maintain their integrity. It is crucial to pay attention to the expiration date on the packaging and discard any unused or expired tablets appropriately. When disposing of the medication, avoid flushing it down the toilet or pouring it into drainage systems. Instead, consult a pharmacist or healthcare professional for guidance on proper disposal methods to ensure environmental safety. Additionally, keep the medication out of children's reach to prevent accidental consumption.

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Following are the quick tips for Carvedilol 12.5mg Tablet:

• Consult your doctor before starting this medication and provide your complete medical history.
• Take the tablet as directed by your doctor, usually twice a day with food.
• Swallow the tablet whole; do not crush, chew, or break it.
• Maintain a consistent schedule for taking the medication to ensure its effectiveness.
• Avoid sudden discontinuation; gradually reduce the dose as advised by your doctor.
• Inform your doctor about all medications you're taking to prevent potential interactions.
• Store the tablets at room temperature, away from moisture and light.