Xatral LP (10mg) 30 Tablets

Alfuzosin 10mg tablets primarily work by selectively blocking alpha-1 adrenergic receptors in the prostate and bladder neck, without causing significant vasodilation. This mechanism of action is specific to the lower urinary tract. When Alfuzosin binds to these receptors, it induces smooth muscle relaxation, which leads to a reduction in the symptoms associated with benign prostatic hyperplasia (BPH). The relaxation of the smooth muscle in the prostate and bladder neck improves urine flow by decreasing the tension in the muscles and connective tissues surrounding the urethra. This action alleviates the obstruction caused by an enlarged prostate, making it easier for urine to flow and reducing the discomfort and urinary retention associated with BPH.

Alfuzosin 10mg

Alpha-blocker.

Tablet

The following are the uses of Alfuzosin 10mg Tablet:

• Used for treating symptoms of benign prostatic hyperplasia (BPH), providing relief from urinary difficulties.
• Used to relax the muscles in the prostate and bladder neck, improving urine flow.
• Used to manage lower urinary tract symptoms associated with an enlarged prostate.
• Used to reduce frequent urination, especially at night, and improve overall urine flow.
• Used to alleviate the feeling of urgency and difficulty in starting urination.
• Used to treat urinary retention caused by an enlarged prostate.
• Used to enhance the patient's quality of life by improving urinary function.

In the case of an overdose of Alfuzosin 10mg Tablets, it is important to recognize the potential symptoms and act swiftly. The patient may experience a sudden drop in blood pressure, leading to dizziness, fainting, or even a rapid heartbeat. If you suspect an overdose, seek medical advice promptly. Timely intervention can help manage the symptoms and ensure the patient's well-being. Contact a healthcare professional or local poison control center for guidance on the appropriate steps to take.

In the case of a missed dose of Alfuzosin 10mg Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you miss several doses, consult your healthcare provider for advice on how to get back on track with your medication regimen. It is crucial to maintain consistency with your medication to ensure its effectiveness.

To take Alfuzosin 10mg Tablet, swallow the tablet whole with a full glass of water, preferably on an empty stomach, once a day, at the same time each day, as directed by your healthcare professional.

Following are the conditions or situations when Alfuzosin 10mg Tablet should not be used:

• Must not be used in individuals with a known allergy or hypersensitivity to Alfuzosin or other quinazoline derivatives.
• Not suitable for patients with severe liver impairment as it may lead to increased drug concentration in the body.
• Contraindicated in individuals with severe kidney disease or end-stage renal disease.
• Should not be used in patients with a rare heart condition called orthostatic hypotension, where there is a sudden drop in blood pressure upon standing.
• Not recommended for individuals with a history of orthostatic syncope, fainting due to sudden drop in blood pressure.
• Must not be used in patients with a rare eye condition called narrow-angle glaucoma, as it can worsen the condition.
• Not suitable for women and children. This medication is generally prescribed for men.

The side effects of Alfuzosin 10mg Tablet may include:

• Dizziness
• Headache
• Drowsiness
• Fatigue
• Nausea
• Stomach pain
• Diarrhea
• Nasal congestion

Following are the precautions and warnings for Alfuzosin 10mg Tablet:

• Not recommended for individuals with known allergies to alfuzosin or similar medications, as severe allergic reactions may occur.
• Patients with moderate to severe liver impairment should exercise caution and consult a doctor, as dosage adjustments might be necessary.
• This medication may cause dizziness and fainting, especially when standing up from a sitting or lying position. Patients should be cautious when performing activities that require alertness.
• Alfuzosin may lead to a condition called orthostatic hypotension, causing low blood pressure. Monitor blood pressure regularly.
• Avoid alcohol consumption as it can worsen side effects such as dizziness and fainting.
• Elderly patients may be more susceptible to the side effects of this medication, particularly dizziness and fainting.
• Alfuzosin should be used with caution in patients with a history of prolonged QT intervals or heart-related conditions. Regular ECG monitoring is advised.

Following are the drug interactions for Alfuzosin 10mg Tablet:

• Alfuzosin may interact with other alpha-blockers (e.g., doxazosin, tamsulosin), increasing the risk of hypotension (low blood pressure) or orthostatic hypotension (sudden dizziness upon standing).
• Caution should be exercised when using Alfuzosin with other antihypertensive medications, such as beta-blockers, ACE inhibitors, or calcium channel blockers, as this may enhance the blood pressure-lowering effects, leading to dizziness or fainting.
• Combining Alfuzosin with strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, ritonavir) may increase the blood levels of Alfuzosin, increasing the risk of side effects like dizziness, fainting, and heart palpitations.
• Concurrent use with nitrates (e.g., nitroglycerin) or phosphodiesterase inhibitors (e.g., sildenafil) may cause a significant drop in blood pressure, leading to dizziness, lightheadedness, or fainting.
• Alfuzosin may interact with drugs that affect liver function, such as cyclosporine, which can increase the concentration of Alfuzosin in the blood, enhancing its effects and side effects.
• Combining Alfuzosin with other medications that cause drowsiness (e.g., sedatives, tranquilizers) may increase the risk of excessive drowsiness or sedation.
• Caution is recommended when using Alfuzosin with diuretics (e.g., furosemide), as this combination may increase the risk of dehydration, leading to low blood pressure or electrolyte imbalances.
• Alcohol consumption may increase the risk of hypotension and dizziness when taking Alfuzosin. It is advisable to limit alcohol intake while using this medication.

Following are the food interactions for Alfuzosin 10mg Tablet:

• Grapefruit and grapefruit juice should be consumed cautiously as they may affect the metabolism of Alfuzosin, potentially leading to increased side effects.
• Alcohol intake should be limited as it can cause excessive blood pressure drop, especially when combined with Alfuzosin, resulting in dizziness and lightheadedness.
• High-fat meals may slightly delay the absorption of Alfuzosin, but it does not significantly impact its overall effectiveness.
• Caffeine-rich foods and beverages might interact with Alfuzosin, potentially causing increased heart rate and blood pressure fluctuations.
• Avoid excessive salt or sodium-rich foods as they can counteract the blood pressure-lowering effect of Alfuzosin.
• Alfuzosin can be taken without regard to meals, but maintaining a consistent routine is advisable for optimal absorption.
• Always ensure you are well-hydrated when taking Alfuzosin to facilitate better dissolution and absorption of the medication.
• Consult your healthcare provider for personalized advice on dietary adjustments while taking Alfuzosin.

Alfuzosin 10mg Tablets should be stored in a secure and dry location, preferably in their original container, at room temperature, away from direct sunlight, moisture, and heat sources. It is crucial to maintain a consistent temperature to preserve the medication's effectiveness. Always keep the tablets out of reach of children and pets to prevent accidental consumption. When disposing of unused or expired tablets, do not throw them in the trash or flush them down the toilet. Instead, contact your pharmacist or local waste management authorities for guidance on proper disposal methods to minimize environmental impact. Regularly check the expiration date on the packaging to ensure the medication's potency and effectiveness. Proper storage and disposal practices are essential for maintaining the integrity of Alfuzosin tablets and promoting medication safety.

Following are the quick tips for Alfuzosin 10mg Tablet:

• Take the tablet as directed by your doctor, typically once daily.
• Consume the tablet whole with a full glass of water, do not crush or chew.
• Take it regularly at the same time each day to maintain a consistent level in your body.
• You can take it with or without food, but taking it with food may reduce stomach upset.
• Avoid grapefruit juice and alcohol as they can affect how the medication works.
• Inform your doctor if you have any pre-existing kidney or liver conditions.
• Store the tablets at room temperature, away from moisture and light.